Detection of Low-Risk and High-Risk Oncogenic Human Papillomavirus in Archived Tissues from ENT Tumors in Burkina Faso
نویسندگان
چکیده
Human papillomavirus (HPV) is classified into high-risk HPV (HR-HPV) and (LR-HPV) according to their oncogenic potential. These viruses can be found in the cervix, vagina, vulva, anus ENT sphere. infections lead benign or malignant tumors which we could find both LR-HPV HR-HPV genotypes. The objective of this study was investigate genotypes archived tissue samples derived from ear, nose, throat (ENT) Ouagadougou, Burkina Faso. One hundred twenty formalin-fixed, paraffin-embedded tissues sphere 26 94 were included. first deparaffinized with xylem. extracted DNA used test for low-risk by Real-Time Multiplex PCR. 57.7% (15/26) 43.61% (41/94) tumors. prevalence infection 46.67% (56/120) all combined. most common 11 (34.28%), 6 (30%), HPV56 (14.28%) 33 (8.57%). There 21.43% (12/56) cases co-infections 10 double 2 triple infection. Both are relatively high prevalence.
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ژورنال
عنوان ژورنال: Journal of Biosciences and Medicines
سال: 2023
ISSN: ['2327-509X', '2327-5081']
DOI: https://doi.org/10.4236/jbm.2023.119015